4.6 Article

Optimizing timing performance of silicon photomultiplier-based scintillation detectors

Journal

PHYSICS IN MEDICINE AND BIOLOGY
Volume 58, Issue 4, Pages 1207-1220

Publisher

IOP PUBLISHING LTD
DOI: 10.1088/0031-9155/58/4/1207

Keywords

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Funding

  1. Stanford Dean's Postdoctoral Fellowship
  2. Netherlands Organization for Scientific Research (NWO)
  3. NIH-NIBIB [R21EB014405]

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Precise timing resolution is crucial for applications requiring photon time-of-flight (ToF) information such as ToF positron emission tomography (PET). Silicon photomultipliers (SiPM) for PET, with their high output capacitance, are known to require custom preamplifiers to optimize timing performance. In this paper, we describe simple alternative front-end electronics based on a commercial low-noise RF preamplifier and methods that have been implemented to achieve excellent timing resolution. Two radiation detectors with L(Y)SO scintillators coupled to Hamamatsu SiPMs (MPPC S10362-33-050C) and front-end electronics based on an RF amplifier (MAR-3SM+), typically used forwireless applications that require minimal additional circuitry, have been fabricated. These detectors were used to detect annihilation photons from a Ge-68 source and the output signals were subsequently digitized by a high speed oscilloscope for offline processing. A coincident resolving time (CRT) of 147 +/- 3 ps FWHM and 186 +/- 3 ps FWHM with 3 x 3 x 5 mm(3) and with 3 x 3 x 20 mm(3) LYSO crystal elements were measured, respectively. With smaller 2 x 2 x 3 mm(3) LSO crystals, a CRT of 125 +/- 2 ps FWHM was achieved with slight improvement to 121 +/- 3 ps at a lower temperature (15 degrees C). Finally, with the 20 mm length crystals, a degradation of timing resolution was observed for annihilation photon interactions that occur close to the photosensor compared to shallow depth-of-interaction (DOI). We conclude that commercial RF amplifiers optimized for noise, besides their ease of use, can produce excellent timing resolution comparable to best reported values acquired with custom readout electronics. On the other hand, as timing performance degrades with increasing photon DOI, a head-on detector configuration will produce better CRT than a side-irradiated setup for longer crystals.

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