4.6 Article

Real-time optical measurement of the dynamic body surface for use in guided radiotherapy

Journal

PHYSICS IN MEDICINE AND BIOLOGY
Volume 57, Issue 2, Pages 415-436

Publisher

IOP PUBLISHING LTD
DOI: 10.1088/0031-9155/57/2/415

Keywords

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Funding

  1. Engineering and Physics Sciences Research Council (EPSRC) [EP/D078415/1]
  2. National Institute of Health Research (NIHR) [K021, HCS/08/028]
  3. National Institute for Health Research [HCS/08/028, K021] Funding Source: researchfish
  4. National Institutes of Health Research (NIHR) [K021, HCS/08/028] Funding Source: National Institutes of Health Research (NIHR)

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Optical measurements are increasingly used in radiotherapy. In this paper we present, in detail, the design and implementation of a multi-channel optical system optimized for fast, high spatial resolution, dynamic body surface measurement in guided therapy. We include all algorithmic modifications and calibration procedures required to create a robust, practical system for clinical use. Comprehensive static and dynamic phantom validation measurements in the radiotherapy treatment room show: conformance with simultaneously measured cone beam CT data to within 1 mm over 62% +/- 8% of the surface and 2 mm over 90% +/- 3%; agreement with the measured radius of a precision geometrical phantom to within 1 mm; and true real-time performance with image capture through to surface display at 23 Hz. An example patient dataset is additionally included, indicating similar performance in the clinic.

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