Journal
PHYSICS IN MEDICINE AND BIOLOGY
Volume 54, Issue 23, Pages 7077-7087Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0031-9155/54/23/003
Keywords
-
Funding
- UK Department of Health
- National Institute for Health Research
- Royal Society
- Institute of Physics and Engineering in Medicine
- National Institute for Health Research [CSA/03/07/017] Funding Source: researchfish
Ask authors/readers for more resources
Raman spectroscopy is a powerful tool for studying biochemical changes in the human body. We describe a miniature, confocal fibre optic probe intended to fit within the instrument channel of a standard medical endoscope. This probe has been optimized for the study of the carcinogenesis process of oesophageal malignancy. The optical design and fabrication of this probe is described including the anisotropic wet etching technique used to make silicon motherboards and jigs. Example spectra of PTFE reference samples are shown. Spectra with acquisition times as low as 2 s from resected oesophageal tissue are presented showing identifiable biochemical changes from various pathologies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available