Journal
PHYSICAL REVIEW E
Volume 88, Issue 2, Pages -Publisher
AMER PHYSICAL SOC
DOI: 10.1103/PhysRevE.88.022706
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Funding
- Forschungszentrum Julich
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We use the wormlike chain model to study supercoiling of DNA under tension and torque. The model reproduces experimental data for a broad range of forces, salt concentrations, and contour lengths. We find a plane of first-order phase transitions ending in a smeared-out line of critical points, the multiplectoneme phase, which is characterized by a fast twist-mediated diffusion of plectonemes and a torque that rises after plectoneme formation with increasing linking number. The discovery of this phase at the same time resolves the discrepancies between existing models and experiment.
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