4.7 Article

Dynamical model for the full stretching curve of DNA

Journal

PHYSICAL REVIEW E
Volume 86, Issue 3, Pages -

Publisher

AMER PHYSICAL SOC
DOI: 10.1103/PhysRevE.86.032902

Keywords

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Funding

  1. Spanish DGICYT Projects [FIS2008-01240, FIS2011-25167]
  2. Fondo Europeo de Desarrollo Regional (FEDER)
  3. European Science Foundation Research Network

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We present a phenomenological dynamical model able to describe the stretching features of the curve of DNA length vs applied force. As concerns the chain, the model is based on the discrete wormlike chain model with elastic modifications, which properly describes the elongation features at low and intermediate forces. The dynamics is developed under a double-well potential with a linear term, which, at high forces, accounts for the narrow transition present in the DNA elongation (overstretching). A quite good agreement between simulation and experiment is obtained.

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