4.7 Article

Competition between multiple totally asymmetric simple exclusion processes for a finite pool of resources

Journal

PHYSICAL REVIEW E
Volume 80, Issue 3, Pages -

Publisher

AMER PHYSICAL SOC
DOI: 10.1103/PhysRevE.80.031142

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Funding

  1. U.S. National Science Foundation [DMR-0705152]

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Using Monte Carlo simulations and a domain-wall theory, we discuss the effect of coupling several totally asymmetric simple exclusion processes (TASEPs) to a finite reservoir of particles. This simple model mimics directed biological transport processes in the presence of finite resources such as protein synthesis limited by a finite pool of ribosomes. If all TASEPs have equal length, we find behavior which is analogous to a single TASEP coupled to a finite pool. For the more generic case of chains with different lengths, several unanticipated regimes emerge. A generalized domain-wall theory captures our findings in good agreement with simulation results.

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