Journal
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
Volume 45, Issue 6, Pages 1159-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cvsm.2015.06.003
Keywords
ADAMTS10; ADAMTS17; Canine; Genetics; Glaucoma; Open-angle; Closed-angle; Lens luxation
Categories
Funding
- Michigan State University Startup Funds
- Glaucoma Research Foundation
- Edward Sheppard and family
- Myers-Dunlap Endowment for Canine Health
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Primary glaucomas are a leading cause of incurable vision loss in dogs. Based on their specific breed predilection, a genetic cause is suspected to be responsible, and affected dogs should be excluded from breeding. Despite the high prevalence of primary glaucomas in dogs, their genetics have been studied in only a small number of breeds. The identification of canine glaucoma disease genes, and the development of genetic tests, will help to avoid the breeding of affected dogs in the future and will allow for earlier diagnosis and potentially more effective therapy.
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