Journal
VASCULAR PHARMACOLOGY
Volume 71, Issue -, Pages 16-23Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.vph.2015.05.015
Keywords
Vasculopathy; Systemic sclerosis; Endothelial cells; Pericytes; Angiogenesis; Vasculogenesis; Reactive oxygen species; Endo-mesenchymal transistion
Categories
Funding
- Faculte de Medecine Paris Descartes
- Assistance Publique Hopitaux de Paris (APHP)
Ask authors/readers for more resources
Vasculopathy is common in patients with connective tissue disease and can be directly implicated in the pathogenesis of the disease. Systemic sclerosis is an auto-immune multiorgan connective tissue disorder characterized by fibrosis of the skin and visceral organs and vascular disease. Micro- and macro-vessels are a direct target of the disease. In this review, we present the various clinical manifestations of the vasculopathy that can be present in SSc patients, and then discuss the various aspects of the pathophysiology of the vascular disorders. (C) 2015 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available