4.6 Article

Evaluation of nonspecific interactions between quantum dots and proteins

Journal

PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Volume 16, Issue 17, Pages 7677-7680

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cp00572d

Keywords

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Funding

  1. National Basic Research Program of China (973 Program) [2011CB933600]
  2. Science Fund for Creative Research Groups of NSFC20921062 [20921062]
  3. NSFC [21275111]
  4. 111 Project [111-2-10]
  5. 3551 Talent Program of the Administrative Committee of East Lake Hi-Tech Development Zone [[2011]137]

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A method based on the AFM and colloidal probe techniques was proposed to directly measure nonspecific interactions between QDs and different proteins with respective sizes and isoelectric points. Results indicated that van der Waals forces were the leading force, while electrostatic interactions also played an important role in nonspecific interactions.

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