4.6 Article

Developments in understanding and controlling self assembly of DNA-functionalized colloids

Journal

PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Volume 15, Issue 9, Pages 3115-3129

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cp43841d

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Funding

  1. Marie Curie Initial Training Network ITN-COMPLOIDS [234810]
  2. Cavendish Laboratory

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In this article we review the latest achievements in understanding and controlling DNA-mediated interactions between colloidal particles. We report the results of experiments, theoretical studies and computer simulations designed to investigate interactions and aggregation/melting behaviour of DNA-functionalized colloids. The unprecedented insight into the physical effects influencing the interactions and their relation with the tunable parameters of the grafted DNA has resulted in innovative DNA coatings, which are expected to solve the decennial issues encountered in the self assembly of DNA-coated colloids.

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