Journal
ULTRASONICS SONOCHEMISTRY
Volume 23, Issue -, Pages 376-384Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ultsonch.2014.10.028
Keywords
Ultrasound; Environmentally friendly methods; N-Alkylation; 1,3-Diazole; Reaction mechanism; Ionic liquids
Categories
Funding
- CNCS Bucharest, Romania [PN-II-TE/0010-79/05.10.2011]
- CERNESIM [POSCCE-0 2.2.1, SMIS-CSNR 13984-901, 257/28.09.2010]
Ask authors/readers for more resources
In this study a straightforward and efficient approach concerning synthesis of 1,3-diazole derivatives under ultrasound (US) irradiation as well as under conventional thermal heating (TH) is presented. N-alkylation under US irradiation may be considered environmentally friendly in terms of higher yields, smaller amounts of solvent used and an overall energy efficiency due to a substantial reduction of reaction times. A comparative study of ultrasound vs. conventional conditions has been performed. Overall, the use of US proved to be more efficient than TH. A possible explanation concerning the different behavior of imidazole and benzimidazole in the N1-alkylation reactions under US irradiation was proposed. (C) 2014 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available