4.4 Article

The ASTRA Toolbox: A platform for advanced algorithm development in electron tomography

Journal

ULTRAMICROSCOPY
Volume 157, Issue -, Pages 35-47

Publisher

ELSEVIER
DOI: 10.1016/j.ultramic.2015.05.002

Keywords

Electron tomography; Reconstruction; ASTRA Toolbox; Dual-axis

Categories

Funding

  1. iMinds ICON MetroCT project
  2. IWT SBO TomFood project
  3. Netherlands Organisation for Scientific Research (NWO) [639.072.005]
  4. European Research Council (ERC) [335078-COLOURATOMS]

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We present the ASTRA Toolbox as an open platform for 3D image reconstruction in tomography. Most of the software tools that are currently used in electron tomography offer limited flexibility with respect to the geometrical parameters of the acquisition model and the algorithms used for reconstruction. The ASTRA Toolbox provides an extensive set of fast and flexible building blocks that can be used to develop advanced reconstruction algorithms, effectively removing these limitations. We demonstrate this flexibility, the resulting reconstruction quality, and the computational efficiency of this toolbox by a series of experiments, based on experimental dual-axis tilt series. (C) 2015 Elsevier B.V. All rights reserved.

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