Global stability and optimal control of an SIRS epidemic model on heterogeneous networks

In this paper, we consider an SIRS epidemic model with vaccination on heterogeneous networks. By constructing suitable Lyapunov functions, global stability of the disease-free equilibrium and the endemic equilibrium of the model is investigated. Also we firstly study an optimally controlled SIRS epidemic model on complex networks. We show that an optimal control exists for the control problem. Finally some examples are presented to show the global stability and the efficiency of this optimal control. These results can help in adopting pragmatic treatment upon diseases in structured populations. (C) 2014 Elsevier B.V. All rights reserved.