Journal
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
Volume 23, Issue -, Pages 281-294Publisher
ELSEVIER
DOI: 10.1016/j.pdpdt.2018.06.023
Keywords
Photosensitiser; Photodynamic therapy; Theranostics; Personalized medicine; PET; Luminescence
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Funding
- Foundation of the Croatian Academy of Sciences and Arts
- European Regional Development Fund (ERDF)
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This review summarises recent research into combining the photosensitizing properties of porphyrins with imaging techniques such as PET and NIR fluorescence for so called theranostic applications, which combine biomedical imaging and therapeutic potential into a single administered substance. The photophysical mechanisms of both the therapeutic and diagnostic properties of porphyrins are discussed, as well as key characteristics that are required in order to deliver the most effective treatment.
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