4.2 Article

Chronic actinic dermatitis in a patient with adult T-cell leukemia

Journal

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE
Volume 24, Issue 3, Pages 147-149

Publisher

WILEY-BLACKWELL
DOI: 10.1111/j.1600-0781.2008.00351.x

Keywords

adult T-cell leukemia; chronic actinic dermatitis; Southern blot analysis

Categories

Ask authors/readers for more resources

A patient with chronic actinic dermatitis showed a leukocytosis with peripheral atypical lymphocytes. Histology of cutaneous eruptions disclosed a dense infiltrate of lymphocytes mixed with large hyperchromatic cells in the dermis and Pautrier-like microabscesses in the epidermis. However, clonal rearrangements of the T-cell receptors were not detected. On the other hand, monoclonal integration of human T-cell lymphotrophic virus type I provirus was found in the peripheral lymphocytes. In the present case, pseudolymphomatous changes occurred in association with adult T-cell leukemia. Southern blot analyses were useful for the correct diagnosis.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available