Journal
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
Volume 10, Issue 1, Pages 109-115Publisher
SPRINGERNATURE
DOI: 10.1039/c0pp00263a
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Funding
- NIH [R01-GM086195, R01-AI061031]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI061031] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM086195] Funding Source: NIH RePORTER
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Through tailored oligonucleotide scaffolds, Ag nanocluster syntheses have yielded thermally and cell-culture medium stable silver cluster-based emitters. Optimizing ssDNA stability has enabled creation of highly concentrated and spectrally pure nanocluster emitters with strong intracellular emission. Both fixed and live-cell staining become possible, and intracellular delivery is demonstrated both through conjugation to cell-penetrating peptides and via microinjection.
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