4.4 Article

Dose dependence of DNA repair in rainbow trout (Oncorhynchus mykiss) larvae exposed to UV-B radiation

Journal

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
Volume 8, Issue 1, Pages 75-81

Publisher

SPRINGERNATURE
DOI: 10.1039/b807469k

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Funding

  1. NSF [DEC-IRCEB-0210972]
  2. NIEHS Center [ES07784]

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We examined survival and DNA damage in rainbow trout larvae (Oncorhynchus mykiss) resulting from a range of sublethal to lethal ultraviolet-B exposures in the presence and absence of photoreactivating radiation. We found that after low, sublethal UV-B exposures trout larvae are quite proficient at photoenzymatic repair but that this capacity decreases exponentially with the total incident UV-B dose. The relationship between the dose dependence of PER and trout development and vulnerability in fisheries and in the natural environment are discussed.

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