4.6 Review

Ion channels in cancer: future perspectives and clinical potential

Related references

Note: Only part of the references are listed.
Review Biology

Role of pHi, and proton transporters in oncogene-driven neoplastic transformation

Stephan Joel Reshkin et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Functional properties of ion channels and transporters in tumour vascularization

Alessandra Fiorio Pla et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

Anne Poder Andersen et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Role of anoctamins in cancer and apoptosis

Podchanart Wanitchakool et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Ion channels and anti-cancer immunity

Gyorgy Panyi et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Cl- and K+ channels and their role in primary brain tumour biology

Kathryn L. Turner et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Article Biology

Targeting ion transport in cancer

E. Oosterwijk et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Potassium channels in cell cycle and cell proliferation

Diana Urrego et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?

Natalia Prevarskaya et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Ion channels and apoptosis in cancer

Carl D. Bortner et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Ion channels and transporters in the development of drug resistance in cancer cells

Else K. Hoffmann et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Regulation of voltage-gated sodium channel expression in cancer: hormones, growth factors and auto-regulation

Scott P. Fraser et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Cell Biology

Oncochannels

Stephan M. Huber

CELL CALCIUM (2013)

Article Cell Biology

Calcium entry via TRPC1 channels activates chloride currents in human glioma cells

Vishnu Anand Cuddapah et al.

CELL CALCIUM (2013)

Article Biochemistry & Molecular Biology

Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice

Roser Ufartes et al.

HUMAN MOLECULAR GENETICS (2013)

Article Neurosciences

Bradykinin-Induced Chemotaxis of Human Gliomas Requires the Activation of KCa3.1 and ClC-3

Vishnu Anand Cuddapah et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Cell Biology

High-grade Glioma Motility Reduced by Genetic Knockdown of KCC3

Kenneth B. Gagnon

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)

Article Cell Biology

The Action of Small GTPases Rab11 and Rab25 in Vesicle Trafficking During Cell Migration

Daniel Kessler et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)

Review Physiology

ROLE OF ION CHANNELS AND TRANSPORTERS IN CELL MIGRATION

Albrecht Schwab et al.

PHYSIOLOGICAL REVIEWS (2012)

Review Physiology

hERG K+ CHANNELS: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE

Jamie I. Vandenberg et al.

PHYSIOLOGICAL REVIEWS (2012)

Article Cell Biology

Ion channels and transporters in cancer. 1. Ion channels and cell proliferation in cancer

Andrea Becchetti

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)

Review Cell Biology

pH Control Mechanisms of Tumor Survival and Growth

Scott K. Parks et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2011)

Article Cell Biology

Serum-Activated K and Cl Currents Underlay U87-MG Glioblastoma Cell Migration

Luigi Catacuzzeno et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2011)

Article Biochemistry & Molecular Biology

Tumor cell-selective apoptosis induction through targeting of KV10.1 via bifunctional TRAIL antibody

Franziska Hartung et al.

MOLECULAR CANCER (2011)

Article Multidisciplinary Sciences

Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis

Yih-Fung Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Cell Biology

Novel roles for hERG K+ channels in cell proliferation and apoptosis

J. Jehle et al.

CELL DEATH & DISEASE (2011)

Review Oncology

Calcium in tumour metastasis: new roles for known actors

Natalia Prevarskaya et al.

NATURE REVIEWS CANCER (2011)

Article Cell Biology

Ca2+ influx via TRPC channels induces NF-κB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells

Prabhakar B. Thippegowda et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)

Article Biochemistry & Molecular Biology

Calcium-sensing receptor activation contributed to apoptosis stimulates TRPC6 channel in rat neonatal ventricular myocytes

Yi-hua Sun et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Biochemistry & Molecular Biology

Calcium uptake mechanisms of mitochondria

Jaime Santo-Domingo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)

Article Biochemistry & Molecular Biology

Constitutive Activity of the Human TRPML2 Channel Induces Cell Degeneration

Shaya Lev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Molecular Interaction and Functional Regulation of ClC-3 by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) in Human Malignant Glioma

Vishnu Anand Cuddapah et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

The potassium channel Ether a go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia

Jasmin R. Agarwal et al.

MOLECULAR CANCER (2010)

Article Multidisciplinary Sciences

Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity

Tetsuro Kusaba et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Pharmacology & Pharmacy

Therapeutic potential of KCa3.1 blockers: recent advances and promising trends

Heike Wulff et al.

Expert Review of Clinical Pharmacology (2010)

Article Cell Biology

cAMP-Dependent Chloride Conductance Evokes Ammonia-Induced Blebbing in the Microglial Cell Line, BV-2

Nina Svoboda et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum

Tomasz Wegierski et al.

EMBO JOURNAL (2009)

Review Biochemistry & Molecular Biology

Physiology and pathophysiology of canonical transient receptor potential channels

Joel Abramowitz et al.

FASEB JOURNAL (2009)

Article Biochemistry & Molecular Biology

Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models

Yuko Iwata et al.

HUMAN MOLECULAR GENETICS (2009)

Review Ophthalmology

TRPV1: Contribution to Retinal Ganglion Cell Apoptosis and Increased Intracellular Ca2+ with Exposure to Hydrostatic Pressure

Rebecca M. Sappington et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)

Article Biochemistry & Molecular Biology

TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons

Hisashi Shirakawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Article Biochemistry & Molecular Biology

TRPV1 mediates cell death in rat synovial fibroblasts through calcium entry-dependent ROS production and mitochondrial depolarization

Fen Hu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Article Biochemistry & Molecular Biology

HGF/SF and menthol increase human glioblastoma cell calcium and migration

Robert Wondergem et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Review Medicine, Research & Experimental

An unexpected role for ion channels in brain tumor metastasis

Harald Sontheimer

EXPERIMENTAL BIOLOGY AND MEDICINE (2008)

Article Cell Biology

Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death

Nola Jean Ernest et al.

JOURNAL OF CELL SCIENCE (2008)

Article Biochemistry & Molecular Biology

Arachidonic acid induces both Na+ and Ca2+ entry resulting in apoptosis

Kwang-Ming Fang et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Neurosciences

ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells

Christa W. Habela et al.

JOURNAL OF NEUROSCIENCE (2008)

Editorial Material Gastroenterology & Hepatology

Calcium signaling and T-type calcium channels in cancer cell cycling

James T. Taylor et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2008)

Review Clinical Neurology

On the hypes and falls in neuroprotection: Targeting the NMDA receptor

Carmen Villmann et al.

NEUROSCIENTIST (2007)

Article Neurosciences

Role of Kir4.1 channels in growth control of glia

Harum Higashimori et al.

Review Biochemistry & Molecular Biology

Potential biochemical therapy of glioma cancer

Li-Tian Yin et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Cell Biology

Cytoplasmic volume condensation is an integral part of mitosis

Christa W. Habela et al.

CELL CYCLE (2007)

Article Cell Biology

New molecular players in capacitative Ca2+ entry

James W. Putney

JOURNAL OF CELL SCIENCE (2007)

Article Pharmacology & Pharmacy

Targeted delivery of antitumoral therapy to glioma and other malignancies with synthetic chlorotoxin (TM-601)

Adam N. Mamelak et al.

EXPERT OPINION ON DRUG DELIVERY (2007)

Review Cell Biology

TRPM channels, calcium and redox sensors during innate immune responses

Pam Massullo et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2006)

Review Cell Biology

Complex functional interaction between integrin receptors and ion channels

Annarosa Arcangeli et al.

TRENDS IN CELL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Dysfunction of regulatory volume increase is a key component of apoptosis

Emi Maeno et al.

FEBS LETTERS (2006)

Article Multidisciplinary Sciences

Orai1 is an essential pore subunit of the CRAC channel

Murali Prakriya et al.

NATURE (2006)

Article Multidisciplinary Sciences

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

Andriy V. Yeromin et al.

NATURE (2006)

Article Cell Biology

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

Christine Peinelt et al.

NATURE CELL BIOLOGY (2006)

Article Multidisciplinary Sciences

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

M. Vig et al.

SCIENCE (2006)

Review Oncology

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis

RA Cardone et al.

NATURE REVIEWS CANCER (2005)

Review Biochemistry & Molecular Biology

Ion channels in cell proliferation and apoptotic cell death

F Lang et al.

JOURNAL OF MEMBRANE BIOLOGY (2005)

Article Multidisciplinary Sciences

Ouabain exacerbates activation-induced cell death in human peripheral blood lymphocytes

MB Esteves et al.

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2005)

Article Neurosciences

Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons

H Lang et al.

JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY (2005)

Article Multidisciplinary Sciences

A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl- channel

T Shimizu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Neurosciences

Cell size-proliferation relationship in rat glioma cells

B Rouzaire-Dubois et al.

Review Physiology

Roles of K+ channels in regulating tumour cell proliferation and apoptosis

ZG Wang

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)

Review Physiology

The 2P-domain K+ channels:: role in apoptosis and tumorigenesis

AJ Patel et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)

Article Neurosciences

Role for calcium-activated potassium channels (BK) in growth control of human malignant glioma cells

AK Weaver et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2004)

Review Cell Biology

Calcium signalling: Dynamics, homeostasis and remodelling

MJ Berridge et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)

Article Pharmacology & Pharmacy

Block of Na+,K+-ATPase and induction of hybrid death by 4-aminopyridine in cultured cortical neurons

XQ Wang et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)

Article Physiology

BK channel openers inhibit migration of human glioma cells

R Kraft et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2003)

Article Biochemistry & Molecular Biology

Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2

J Deshane et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Cell Biology

Role of Ca2+-activated K+ channels in human erythrocyte apoptosis

PA Lang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)

Article Biochemistry & Molecular Biology

Comparison between Ca2+-induced scrambling of various fluorescently labelled lipid analogues in red blood cells

DWC Dekkers et al.

BIOCHEMICAL JOURNAL (2002)

Article Biochemistry & Molecular Biology

Apoptosis, cell volume regulation and volume-regulatory chloride channels

Y Okada et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY (2001)

Article Biochemistry & Molecular Biology

Plasma membrane depolarization without repolarization is an early molecular event in anti-Fas-induced apoptosis

CD Bortner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Review Cell Biology

The versatility and universality of calcium signalling

MJ Berridge et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2000)

Article Multidisciplinary Sciences

Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis

E Maeno et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Review Cell Biology

Cell volume in the regulation of cell proliferation and apoptotic cell death

F Lang et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2000)