Journal
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
Volume 367, Issue 1592, Pages 1112-1122Publisher
ROYAL SOC
DOI: 10.1098/rstb.2011.0206
Keywords
chaperone-usher; pilus biogenesis; host-pathogen interactions
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Funding
- European Molecular Biology Organization (EMBO) [ALTF 745-2009]
- MRC [252616, 85602]
- Wellcome Trust [082227]
- Medical Research Council [G0800002] Funding Source: researchfish
- MRC [G0800002] Funding Source: UKRI
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Up to eight different types of secretion systems, and several more subtypes, have been described in Gram-negative bacteria. Here, we focus on the diversity and assembly mechanism of one of the best-studied secretion systems, the widespread chaperone-usher pathway known to assemble and secrete adhesive surface structures, called pili or fimbriae, which play essential roles in targeting bacterial pathogens to the host.
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