Journal
PHARMACEUTICAL RESEARCH
Volume 25, Issue 10, Pages 2205-2215Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11095-008-9587-2
Keywords
forensic; non-invasive; pharmaceutical; process control; Raman
Funding
- EPSRC [EP/D037662/1]
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This article reviews emerging Raman techniques (Spatially Offset and Transmission Raman Spectroscopy) for non-invasive, sub-surface probing in process control and forensic applications. New capabilities offered by these methods are discussed and several application examples are given including the non-invasive detection of counterfeit drugs through blister packs and opaque plastic bottles and the rapid quantitative analysis of the bulk content of pharmaceutical tablets and capsules without sub-sampling.
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