Journal
PHARMACEUTICAL CHEMISTRY JOURNAL
Volume 44, Issue 11, Pages 628-631Publisher
SPRINGER
DOI: 10.1007/s11094-011-0533-y
Keywords
Fluvoxamine; HPLC-UV; derivatization; 1,2-naphthoquinone-4-sulfonic acid sodium salt; chromato-mass spectrometry; tandem HPLC-MS; therapeutic drug monitoring
Categories
Ask authors/readers for more resources
A highly sensitive and reproducible method for assay of fluvoxamine in biological samples using HPLC combined with various detection methods ( spectrophotometry and tandem mass spectrometry) was developed. These methods were completely interchangeable and correlation analysis demonstrated high consistency in the results obtained by different detection methods: the Pearson correlation coefficient was 0.982 (p < 0.0001) and the slope of the regression line was close to unity. The methods were suitable for routine therapeutic monitoring of fluvoxamine in patients' serum.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
