Hepatoprotective and antioxidant activities of Tamarix nilotica flowers

Objective: aEuro,This study aimed to evaluate the hydro-alcoholic extract (80%) of T. nilotica flowers for hepatoprotective and antioxidant activities. Materials and methods: aEuro,Hepatoprotective activity was assessed using carbon tetrachloride--induced hepatic injury in rats by monitoring biochemical parameters. Antioxidant activity was evaluated in alloxan-induced diabetic rats. Biochemical markers of hepatic damage such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), and tissue glutathione were determined in all groups. Results and conclusion: aEuro,Carbon tetrachloride (5 mL/kg body weight) enhanced the SGOT, SGPT, and ALP levels. There was a marked reduction in tissue glutathione level in diabetic rats. The hydro-alcoholic extract of T. nilotica (100 mg/kg body weight) ameliorated the adverse effects of carbon tetrachloride and returned the altered levels of biochemical markers near to the normal levels.