Related references
Note: Only part of the references are listed.Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts
Kenneth B. Gagnon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2013)
High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells
Monica Carmosino et al.
BMC CELL BIOLOGY (2013)
Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy
Sanaz Eftekhari et al.
EPILEPSIA (2013)
Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers
Jose Ponce-Coria et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
Na+-K+-2Cl- cotransporter type 2 trafficking and activity: The role of interacting proteins
Monica Carmosino et al.
BIOLOGY OF THE CELL (2012)
The role of the kidney in salt-sensitive hypertension
Francesco Trepiccione et al.
CLINICAL AND EXPERIMENTAL NEPHROLOGY (2012)
Loop Diuretic and Ion-binding Residues Revealed by Scanning Mutagenesis of Transmembrane Helix 3 (TM3) of Na-K-Cl Cotransporter (NKCC1)
Suma Somasekharan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Amino Acid-Polyamine-Organocation Superfamily
Foon H. Wong et al.
JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY (2012)
Sortilin and SorLA Regulate Neuronal Sorting of Trophic and Dementia-Linked Proteins
Lone Tjener Pallesen et al.
MOLECULAR NEUROBIOLOGY (2012)
MOLECULAR PHYSIOLOGY OF SPAK AND OSR1: TWO STE20-RELATED PROTEIN KINASES REGULATING ION TRANSPORT
Kenneth B. Gagnon et al.
PHYSIOLOGICAL REVIEWS (2012)
Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1
Chang-Yi Cui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Expression of Na+-K+-2Cl- Cotransporter 1 Is Epigenetically Regulated During Postnatal Development of Hypertension
Hyun-Min Cho et al.
AMERICAN JOURNAL OF HYPERTENSION (2011)
Kinetics of hyperosmotically stimulated Na-K-2Cl cotransporter in Xenopus laevis oocytes
Eric Delpire et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine
Robert L. Jakab et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)
A SPAK Isoform Switch Modulates Renal Salt Transport and Blood Pressure
James A. McCormick et al.
CELL METABOLISM (2011)
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
Beatrice M. Filippi et al.
EMBO JOURNAL (2011)
Regulatory Activation Is Accompanied by Movement in the C Terminus of the Na-K-Cl Cotransporter (NKCC1)
Michelle Y. Monette et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Secretory Carrier Membrane Protein 2 Regulates Exocytic Insertion of NKCC2 into the Cell Membrane
Nancy Zaarour et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways
Ciaran Richardson et al.
JOURNAL OF CELL SCIENCE (2011)
The WNKs: Atypical Protein Kinases With Pleiotropic Actions
James A. McCormick et al.
PHYSIOLOGICAL REVIEWS (2011)
NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension
Monica Carmosino et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2011)
Impaired phosphorylation of Na+-K+-2Cl- cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome
Shih-Hua Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Role of NH3 and NH4+ transporters in renal acid-base transport
I. David Weiner et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Molecular regulation of NKCC2 in the thick ascending limb
Gustavo R. Ares et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Multiple Pathways for Protein Phosphatase 1 (PP1) Regulation of Na-K-2Cl Cotransporter (NKCC1) Function THE N-TERMINAL TAIL OF THE Na-K-2Cl COTRANSPORTER SERVES AS A REGULATORY SCAFFOLD FOR Ste20-RELATED PROLINE/ALANINE-RICH KINASE (SPAK) AND PP1
Kenneth B. Gagnon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Molecular determinants of hyperosmotically activated NKCC1-mediated K+/K+ exchange
Kenneth B. Gagnon et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
SPAK-Knockout Mice Manifest Gitelman Syndrome and Impaired Vasoconstriction
Sung-Sen Yang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Macula Densa Sensing and Signaling Mechanisms of Renin Release
Janos Peti-Peterdi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
SORLA/SORL1 Functionally Interacts with SPAK To Control Renal Activation of Na+-K+-Cl- Cotransporter 2
Juliane Reiche et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
MAL/VIP17, a New Player in the Regulation of NKCC2 in the Kidney
Monica Carmosino et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
AP2/EREBP transcription factors are part of gene regulatory networks and integrate metabolic, hormonal and environmental signals in stress acclimation and retrograde signalling
Karl-Josef Dietz et al.
PROTOPLASMA (2010)
cAMP Stimulates Apical Exocytosis of the Renal Na+-K+-2Cl- Cotransporter NKCC2 in the Thick Ascending Limb ROLE OF PROTEIN KINASE A
Paulo S. Caceres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Ste20 Kinases Ste20-related Proline-Alanine-rich Kinase and Oxidative-stress Response 1 Regulate NKCC1 Function in Sensory Neurons
Yang Geng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A Conserved Hydrophobic Tetrad near the C Terminus of the Secretory Na+-K+-2Cl- Cotransporter (NKCC1) Is Required for Its Correct Intracellular Processing
Akihiro Nezu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Protein structure prediction on the Web: a case study using the Phyre server
Lawrence A. Kelley et al.
NATURE PROTOCOLS (2009)
Physiology of Cell Volume Regulation in Vertebrates
Else K. Hoffmann et al.
PHYSIOLOGICAL REVIEWS (2009)
Potassium Ion Movement in the Inner Ear: Insights from Genetic Disease and Mouse Models
Anselm A. Zdebik et al.
PHYSIOLOGY (2009)
Regulated acid-base transport in the collecting duct
Carsten A. Wagner et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2
Eric Delpire et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Induction of Na+/K+/2Cl- cotransporter expression mediates chronic potentiation of intestinal epithelial Cl- secretion by EGF
Fiona O'Mahony et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus
Lei Zhu et al.
EPILEPSY RESEARCH (2008)
PKCδ acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells
Laura Smith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABAA signaling in neonatal neurons
Audrey C. Brumback et al.
JOURNAL OF NEUROSCIENCE (2008)
Exon Loss Accounts for Differential Sorting of Na-K-Cl Cotransporters in Polarized Epithelial Cells
Monica Carmosino et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
CGMP decreases surface NKCC2 levels in the thick ascending limb: role of phosphodiesterase 2 (PDE2)
Gustavo R. Ares et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent
Pia Welker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance
Hayo Castrop et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL
K. Mutig et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
NKCC1 does not accumulate chloride in developing retinal neurons
Ling-Li Zhang et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK)
Scott A. Fraser et al.
BIOCHEMICAL JOURNAL (2007)
Activator protein-2 in carcinogenesis with a special reference to breast cancer - A mini review
Johanna M. Pellikainen et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone
Puneet Garg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation
Kenneth B. E. Gagnon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Renal function in mice with targeted disruption of the A isoform of the Na-K-2Cl co-transporter
Mona Oppermann et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter
Kenneth B. E. Gagnon et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2007)
The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion
Diana Pacheco-Alvarez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Transcriptional repression of Na-K-2Cl cotransporter NKCC1 by hypoxia-inducible factor-1
Juan C. Ibla et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Subtractive hybridization unravels a role for the ion cotransporter NKCC1 in the murine intestinal pacemaker
Mira Wouters et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
Activity of the renal Na+-K+-2Cl- cotransporter is reduced by mutagenesis of N-glycosylation sites:: role for protein surface charge in Cl- transport
A Paredes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Vascular tone control in humans:: Insights from studies in Bartter's/Gitelman's syndromes
LA Calò
KIDNEY INTERNATIONAL (2006)
Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4
KBE Gagnon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Molecular mechanisms and regulation of furosemide-sensitive Na-K-Cl cotransporters
Ignacio Gimenez
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2006)
Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2)
I Giménez et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Functional domains of the epithelial sodium channel
J Loffing et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
NKCC1 transporter facilitates seizures in the developing brain
VI Dzhala et al.
NATURE MEDICINE (2005)
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
AC Vitari et al.
BIOCHEMICAL JOURNAL (2005)
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
A Yamashita et al.
NATURE (2005)
Altered expression of renal apical plasma membrane Na+ transporters in the early phase of genetic hypertension
G Capasso et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons
J Reisert et al.
NEURON (2005)
SPAK kinase is a substrate and target of PKCθ in T-cell receptor-induced AP-1 activation pathway
YQ Li et al.
EMBO JOURNAL (2004)
Self-interacting domains in the C terminus of a cation-Cl- cotransporter described for the first time
CF Simard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
J Boudeau et al.
EMBO JOURNAL (2003)
Acid pH increases the stability of BSC1/NKCC2 mRNA in the medullary thick ascending limb
Z Karim et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
BFX Dowd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein
I Giménez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ammonium transport and pH regulation by K+-Cl- cotransporters
MJ Bergeron et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)
Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders
AW Krug et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2003)
Mutations in the human Na-K-2Cl cotransporter (NKCC2) identified in Bartter syndrome type I consistently result in nonfunctional transporters
PGJF Starremans et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Chronic intestinal pseudoobstruction associated with altered interstitial cells of Cajal networks
AE Feldstein et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2003)
Cation chloride cotransporters interact with the stress-related kinases Ste20-kelated proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
K Piechotta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of A-type γ-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons
RA DeFazio et al.
MOLECULAR ENDOCRINOLOGY (2002)
Enteric nerves and interstitial cells of Cajal are altered in patients with slow-transit constipation and megacolon
T Wedel et al.
GASTROENTEROLOGY (2002)
A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1
RB Darman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of the Na-K-Cl cotransporter NKM detected with a phospho-specific antibody
AW Flemmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Localization of gamma-aminobutyric acid A receptor subunits in the rat spiral ganglion and organ of corti
Y Yamamoto et al.
ACTA OTO-LARYNGOLOGICA (2002)
Quantitation of Na+-K+-2Cl- cotransport splice variants in human tissues using kinetic polymerase chain reaction
CRT Vibat et al.
ANALYTICAL BIOCHEMISTRY (2001)
Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter
RB Darman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Transmembrane topology of the secretory Na+-K+-2Cl- cotransporter NKCC1 studied by in vitro translation
T Gerelsaikhan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
MP Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Uncompensated polyuria in a mouse model of Bartter's syndrome
N Takahashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The structural unit of the secretory Na+-K+-2Cl- cotransporter (NKCCl) is a homodimer
ML Moore-Hoon et al.
BIOCHEMISTRY (2000)
Failure of spermatogenesis in mouse lines deficient in the Na+-K+-2Cl- cotransporter
AJ Pace et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)