Journal
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
Volume 92, Issue 1, Pages 15-18Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.pestbp.2008.03.013
Keywords
sodium cyanide; catalase; hydrogen peroxide; C. carpio; antioxidant status; environmental situations; biomarker
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The Cyprinus carpio fingerlings on exposure to lethal (1 mg/L) and sub lethal concentrations (0.066 mg/L) of sodium cyanide showed inhibition in the activity of catalase. The disruption of catalase activity in freshwater fish, C. carpio is demonstrated in the present study using UV-visible spectrophotometer at 240 nm using hydrogen peroxide as a substrate. It suggests toxic effects of sodium cyanide and consequent accumulation of hydrogen peroxide in the functionally different tissues namely, liver, gill, muscle and brain. This might lead to cellular damages, and create widespread physiological disturbance. The results suggest that catalase activity can be a good diagnostic tool for sodium cyanide toxicity in biomonitoring programme. (C) 2008 Elsevier Inc. All rights reserved.
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