4.7 Article

Discovery of highly insecticidal synthetic spinosyn mimics-CAMD enabled de novo design simplifying a complex natural product

Journal

PEST MANAGEMENT SCIENCE
Volume 75, Issue 2, Pages 309-313

Publisher

WILEY
DOI: 10.1002/ps.5217

Keywords

spinosyn; natural product; insecticide discoverymacrolidesynthetic; mimics

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Simplifying complex natural products: Computer modeling-based design leads to highly insecticidal, chemically simpler synthetic mimics of the spinosyn natural products that are active in the field. (c) 2018 Society of Chemical Industry

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