Journal
PERIODONTOLOGY 2000
Volume 58, Issue -, Pages 153-160Publisher
WILEY
DOI: 10.1111/j.1600-0757.2011.00423.x
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Our understanding of the causes of periodontal disease have two major competing paradigms: one that focuses on local etiologic factors and one that focuses on remote host-level factors. We provide a historical overview of local and remote cause hypotheses and discuss some key reasons why the local cause hypothesis has become dominant.
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