Journal
TRENDS IN PARASITOLOGY
Volume 31, Issue 6, Pages 260-269Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2015.03.008
Keywords
Borrelia miyamotoi; tick-borne relapsing fever; Ixodes
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Borrelia miyamotoi is a relapsing fever spirochete that has only recently been identified as a human pathogen. Borrelia miyamotoi is genetically and ecologically distinct from Borrelia burgdorferisensu lato, while both are present in Ixodes ticks. Over 50 patients with an acute febrile illness have been described with a B. miyamotoi infection, and two infected immunocompromised patients developed a meningoencephalitis. Seroprevalence studies indicate exposure in the general population and in specific risk groups, such as patients initially suspected of having human granulocytic anaplasmosis. Here, we review the available literature on B. miyamotoi, describing its presence in ticks, reservoir hosts, and humans, and discussing its potential impact on public health.
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