Journal
PEDIATRICS
Volume 132, Issue 2, Pages E526-E530Publisher
AMER ACAD PEDIATRICS
DOI: 10.1542/peds.2011-1900
Keywords
autoimmune hepatitis; children; treatment; rituximab
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Autoimmune hepatitis is a severe liver disease in which similar to 10% of patients do not respond to standard treatment. We describe a new rescue therapy using anti-CD20 monoclonal antibodies (rituximab). Complete remission was obtained and maintained by using low doses of immunosuppressive drugs with repeated anti-CD20 infusions.
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