Journal
TRENDS IN MOLECULAR MEDICINE
Volume 21, Issue 9, Pages 530-532Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.molmed.2015.06.006
Keywords
INPP4B; phosphoinositide; PI3K; Akt; oncogene; tumor suppressor
Ask authors/readers for more resources
INPP4B acts as a tumor suppressor in various epithelial cancers by inhibiting PI3K/Akt signaling. Unexpectedly, tumor-promoting features of INPP4B in leukemia and breast cancer have been recently uncovered. In this spotlight, we discuss the seemingly paradoxical nature of INPP4B-mediated signaling in cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
