4.6 Editorial Material

The Regulatory T Cell: Jack-Of-All-Trades

Journal

TRENDS IN IMMUNOLOGY
Volume 36, Issue 12, Pages 756-758

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ELSEVIER SCI LTD
DOI: 10.1016/j.it.2015.10.002

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Foxp3(+) regulatory T (Treg) cells suppress auto-reactive and inflammatory T cells to maintain immune homeostasis. In a recent study, Rudensky and colleagues demonstrate the ability of Treg cells to facilitate tissue repair, a non-canonical Treg cell function accomplished by amphiregulin and mediated by cytokines interleukin (IL)-18 and IL-33.

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