4.7 Review

Application of microfluidic lab-on-a-chip for the detection of mycotoxins in foods

Journal

TRENDS IN FOOD SCIENCE & TECHNOLOGY
Volume 46, Issue 2, Pages 252-263

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tifs.2015.09.005

Keywords

Mycotoxins; Microfluidic lab-on-a-chip; Agricultural and food safety; Biosensors; Fabrication methods

Funding

  1. Natural Sciences and Engineering Research Council of Canada [NSERC RGPIN-2014-05487, NSERC EGP-485163-15, NSERC EGP-479494-15, NSERC EGP-467970-14, NSERC EGP-463727-14]

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Background: Various foods are susceptible to contamination and adulteration with mycotoxins, presenting serious health risks to humans. Microfluidic lab-on-a-chip devices could integrate and miniaturize versatile functions from sample preparation to detection, showing great potential in rapid, accurate, and high-throughput detection of mycotoxins. Scope and approach: This review focuses on the application of microfluidic lab-on-a-chip platforms to detect mycotoxins in foods. Fabrication processes and major components of microfluidic devices, as well as separation and detection methods integrated with lab-on-a-chip systems are summarized and discussed. Finally, challenges and future research directions in the development of microfluidic devices to detect mycotoxins are highlighted. Key findings and conclusions: Microfluidic lab-on-a-chip devices have a great potential for accurate and high-throughput detection of mycotoxins in agricultural and food products. (C) 2015 Elsevier Ltd. All rights reserved.

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