4.6 Article

Structural MRI in Autism Spectrum Disorder

Journal

PEDIATRIC RESEARCH
Volume 69, Issue 5, Pages 63R-68R

Publisher

INT PEDIATRIC RESEARCH FOUNDATION, INC
DOI: 10.1203/PDR.0b013e318212c2b3

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Funding

  1. National Institute of Aging [R01 AG13743]
  2. National Institute of Mental Health
  3. National Cancer Institute
  4. NIH [R03 EB009310]
  5. University of Pennsylvania
  6. China Scholarship Council [2008101370]
  7. National Natural Science foundation of China [30570655]
  8. Scientific Research Foundation of Graduate School of Southeast University [YBJJ1011]

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Magnetic resonance (MR) examination provides a powerful tool for investigating brain structural changes in children with autism spectrum disorder (ASD). We review recent advances in the understanding of structural MR correlates of ASD. We summarize findings from studies based on voxel-based morphometry, surface-based morphometry, tensor-based morphometry, and diffusion-tensor imaging. Finally, we discuss diagnostic models of ASD based on MR-derived features. (Pediatr Res 69: 63R-68R, 2011)

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