Journal
TRENDS IN BIOTECHNOLOGY
Volume 33, Issue 1, Pages 43-54Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2014.11.005
Keywords
lignocellulosic lipids; single-cell oil; biorefinery; microbial lipids
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Although single-cell oil (SCO) has been studied for decades, lipid production from lignocellulosic biomass has received substantial attention only in recent years as biofuel research moves toward producing drop-in fuels. This review gives an overview of the feasibility and challenges that exist in realizing microbial lipid production from lignocellulosic biomass in a biorefinery. The aspects covered here include biorefinery technologies, the microbial oil market, oleaginous microbes, lipid accumulation metabolism, strain development, process configurations, lignocellulosic lipid production, technical hurdles, lipid recovery, and technoeconomics. The lignocellulosic SCO-based biorefinery will be feasible only if a combination of low- and high-value lipids are coproduced, while lignin and protein are upgraded to high-value products.
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