Journal
TRENDS IN BIOTECHNOLOGY
Volume 33, Issue 7, Pages 371-373Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2015.03.011
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Cobalamine cofactors (vitamin B12) are complex organometallic molecules that are crucial for the activity of a variety of different interesting enzymes such as isomerases, methyltransferases, and dehalogenases. Developments in understanding the structure, mechanism, and role in nature of methylcobalamin-dependent methyltransferases make them excellent candidates for biotechnological applications such as biocatalytic dealkylation.
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