Journal
PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 31, Issue 12, Pages 1269-1271Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e31826a3eaf
Keywords
vancomycin; Staphylococcus aureus; therapeutic drug monitoring
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Despite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use in children 1 month to 12 years of age. Initial and adjusted target trough vancomycin concentrations in serum were infrequently achieved regardless of the dosing schedule. Currently recommended trough concentrations need to be re-examined with a more detailed pharmacokinetic study in children.
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