Journal
PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 29, Issue 12, Pages 1133-1135Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e3181ed18ab
Keywords
diarrhea; rotavirus; rotavirus vaccine; vaccine effectiveness
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Funding
- Centers for Disease Control and Prevention
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Fecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effectiveness against severe rotavirus gastroenteritis was sustained during the first 2 years of the vaccination program. Overall 3-dose effectiveness was 83% to 86%; it was 92% to 93% among children 6 to 11 months of age and 78% to 84% among children >= 12 months of age.
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