4.5 Article

MULTIDRUG-RESISTANT ENTEROCOCCUS FAECIUM MENINGITIS IN A TODDLER CHARACTERIZATION OF THE ORGANISM AND SUCCESSFUL TREATMENT WITH INTRAVENTRICULAR DAPTOMYCIN AND INTRAVENOUS TIGECYCLINE

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 29, Issue 4, Pages 379-381

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e3181c806d8

Keywords

vancomycin-resistant Enterococcus; tigecycline; daptomycin; meningitis; children

Funding

  1. NIH [5T32HD007233-28]

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A case of enterococcal meningitis in a toddler is presented. The organism was highly resistant to all drugs previously used for pediatric Gram-positive meningitis. She was successfully treated with intraventricular and intravenous daptomycin and intravenous tigecycline. The organism was characterized as a member of CC17, a notorious emerging nosocomial clone of Enterococcus faecium.

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