Journal
PEDIATRIC HEMATOLOGY AND ONCOLOGY
Volume 31, Issue 6, Pages 568-573Publisher
TAYLOR & FRANCIS INC
DOI: 10.3109/08880018.2013.831961
Keywords
acute lymphoblastic leukemia; bone scan; chronic myeloid leukemia; hyperviscosity; MRI; osteonecrosis
Categories
Funding
- Max Foundation
Ask authors/readers for more resources
A 12-year-old female is reported who presented with right hip pain for 6 months. With massive splenohepatomegaly and leukocytosis, CML was suspected and confirmed on bone-marrow examination and cytogenetics. Further investigations confirmed avascular necrosis (AVN) of the right femoral head. CML was treated by hydroxyurea, followed by imatinib. AVN was managed conservatively; patient demonstrated progressive improvement, though a mild limp in the gait was persisting at 22 months. AVN as the initial manifestation of CML is a rarity. Leukostasis is considered to be the pathophysiological mechanism. In view of the rarity, a case is reported, along with compilation of previously reported cases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available