4.1 Article

Organophosphate Poisoning-Induced Acute Renal Failure

Journal

PEDIATRIC EMERGENCY CARE
Volume 29, Issue 5, Pages 646-647

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PEC.0b013e31828e9e45

Keywords

organophosphate intoxication; chlorpyrifos; renal failure; continuous venovenous hemofiltration

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Background: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear. Case: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function. Conclusions: Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.

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