Journal
PEDIATRIC DIABETES
Volume 15, Issue 4, Pages 277-286Publisher
WILEY-BLACKWELL
DOI: 10.1111/pedi.12154
Keywords
diabetes; diabetic ketoacidosis; management guidelines
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The current version of the International Society of Pediatric and Adolescent Diabetes (ISPAD) guidelines for management of diabetic ketoacidosis (DKA) is largely based on the Lawson Wilkins Pediatric Endocrine Society/European Society of Pediatric Endocrinology (LWPES/ESPE) consensus statement on DKA in children and adolescents published in 2004. This article critically reviews and presents the most pertinent new data published in the past decade, which have implications for diagnosis and management. Four elements of the guidelines warrant modification: (i) The definition of DKA; (ii) insulin therapy; (iii) water and salt replacement; and (iv) blood ss-hydroxybutyrate measurements for the management of DKA.
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