4.2 Article

Autism: Definition, Neurobiology, Screening, Diagnosis

Journal

PEDIATRIC CLINICS OF NORTH AMERICA
Volume 55, Issue 5, Pages 1129-+

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pcl.2008.07.005

Keywords

Autism; Genetics; Epidemiology; Synapse; Connectivity; Sensorimotor deficits; Brain imaging; Electrophysiology; Immunology

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Autism (ie, the autism spectrum disorders) is now recognized in 1 in 150 children. This article highlights the definition, neurobiology, screening, and diagnosis of autism. The genetics, immunology, imaging, and neurophysiology of autism are reviewed, with particular emphasis on areas that impact pediatricians. Early recognition of the social deficits that characterize autism is key to maximizing the potential of these children.

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