Journal
PATHOLOGY INTERNATIONAL
Volume 59, Issue 10, Pages 744-747Publisher
WILEY
DOI: 10.1111/j.1440-1827.2009.02437.x
Keywords
adenocarcinoma; autoimmune pancreatitis; lymphoplasmacytic sclerosing pancreatitis; pancreas
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An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells throughout the mass. A small invasive ductal adenocarcinoma was observed in the center of the area affected by LPSP. The present case suggests that LPSP may be closely related to carcinogenesis of the pancreas.
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