Journal
PATHOLOGIE BIOLOGIE
Volume 60, Issue 6, Pages 399-405Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.patbio.2012.03.002
Keywords
Acanthamoeba spp.; Naegleria fowleri; Balamuthia mandrillaris; Sappinia sp.; Epidemiology; Ecology; Human infections
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Free-living amoebae are widely distributed in soil and water. Small number of them was implicated in human disease: Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris and Sappinia diploidea. Some of the infections were opportunistic, occurring mainly in immunocompromised hosts (Acanthamoeba and Balamuthia encephalitis) while others are non opportunistic (Acanthamoeba keratitis, Naegleria meningoencephalitis and some cases of Balamuthia encephalitis). Although, the number of infections caused by these amoebae is low, their diagnosis was still difficult to confirm and so there was a higher mortality, particularly, associated with encephalitis. In this review, we present some information about epidemiology, ecology and the types of diseases caused by these pathogens amoebae. (C) 2012 Elsevier Masson SAS. All rights reserved.
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