Journal
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
Volume 32, Issue 5, Pages 515-523Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ppsc.201400219
Keywords
fluorescence bioimaging; graphene quantum dots; in vitro; in vivo; therapy
Funding
- NSF [CMMI-1400274, CMMI-1266295, AIR-IIP-1343270, DMR 1106160]
- AFOSR [FA9550-12-1-0069, FA9550-12-1-0037]
- DAGSI [RQ20-CWRU-13-4]
- DOD-Army [W911NF-11-1-0209]
- State Key Laboratory of Organic-Inorganic Composites
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Graphene quantum dots (GQDs) have attracted tremendous attention in recent years. In this review, the recent developments are summarized in the synthesis, edge functionalization, and cyctotoxicity of GQDs, followed by presenting a focused overview on their current applications for in vitro fluorescence imaging in cells and tissues as well as in vivo macroscopic and microscopic imaging in animals. Challenges and opportunities in the development of GQDs for bioimaging are also discussed.
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