Journal
PARKINSONISM & RELATED DISORDERS
Volume 15, Issue -, Pages S87-S92Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1353-8020(09)70789-8
Keywords
Parkinson's disease; Non-motor symptoms; Depression; Dementia
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Funding
- Center for Regenerative Therapies Dresden
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Parkinson's disease (PD) is the second most common neurodegenerative disease and primarily considered as a movement disorder defined by the presence of motor symptoms, such as bradykinesia, tremor and rigidity. However, it is nowadays widely recognized that in addition there is impairment of cognitive function, mood and the autonomic nervous system in a high percentage of PD patients, which is sometimes even more harming quality of life. These symptoms not only occur during the course of the disease but may even precede the onset of motor symptoms. Typical examples of non-motor features of PD are depression, constipation, REM sleep behaviour disorder, and hyposmia. (C) 2009 Elsevier Ltd. All rights reserved.
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