Journal
PARKINSONISM & RELATED DISORDERS
Volume 14, Issue 2, Pages 166-169Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2007.03.003
Keywords
amantadine; corneal endothelial dysfunction; side effects; Parkinson's disease
Categories
Ask authors/readers for more resources
A 61-year-old man with Parkinson's disease (PD) developed sudden-onset visual impairment after initiation of amantadine treatment. Ophthalmologic examination revealed corneal endothelial edema. Discontinuation of amantadine resulted in rapid improvement of visual acuity. A review of the literature indicated only a few reports of amantadine-associated corneal dysfunction in patients with neurological disorders as well as influenza syndrome, but none with PD. Amantadine-associated visual impairment in PD could be possibly overlooked.. since PD mainly affects elderly people who often develop aging-related ocular changes. The present report alerts neurologists and physicians in general to the peculiar oplithalmologic side effect of amantadine. (C) 2007 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available