Journal
PARASITOLOGY RESEARCH
Volume 107, Issue 3, Pages 501-507Publisher
SPRINGER
DOI: 10.1007/s00436-010-1927-6
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Funding
- National Basic Research Program of China [2007CB513104]
- National Natural Science Foundation of China [30972178]
- National Special Research Program [200803017]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT0723]
- National Key Technology R&D Program of China [2010BAD04B01]
- Academy of Military Medical Sciences [YCX0901]
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MicroRNAs (miRNAs) are a class of endogenous non-coding small RNAs regulating gene expression in eukaryotes at the post-transcriptional level. The complex life cycles of parasites may require the ability to respond to environmental and developmental signals through miRNA-mediated gene expression. Over the past 17 years, thousands of miRNAs have been identified in the nematode Caenorhabditis elegans and other parasites. Here, we review the current status and potential functions of miRNAs in protozoan, helminths, and arthropods, and propose some perspectives for future studies.
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