Journal
PARASITOLOGY RESEARCH
Volume 104, Issue 4, Pages 869-874Publisher
SPRINGER
DOI: 10.1007/s00436-008-1269-9
Keywords
-
Categories
Funding
- Japan Society for Promotion of Sciences [19580355, 20570090]
- Morinaga Service Foundation, Tokyo, Japan
- Grants-in-Aid for Scientific Research [20570090, 19580355] Funding Source: KAKEN
Ask authors/readers for more resources
Four hyper-variable regions (HVR-I to -IV) found in 18S ribosomal DNA sequences were compared among 34 isolates of 15 species of the genus Strongyloides to evaluate their diagnostic value. HVR-I to -III were short, and plural species exhibit the same nucleotide arrangement. Meanwhile, HVR-IV had 23 to 39 nucleotides, showing species-specific arrangements, except Strongyloides ransomi and Strongyloides venezuelensis, which had the same nucleotide sequence in HVR-IV but were readily distinguished by the difference in HVR-I and -III. Isolates of Strongyloides stercoralis from humans of USA, Japan, and Philippines, chimpanzees, and dogs had an identical sequence in this region. Meanwhile, intraspecific polymorphism in HVR-IV nucleotide arrangement was observed among isolates of Strongyloides fuelleborni and Strongyloides callosciureus, presumably reflecting process of geographical dispersal and adaptation to the hosts.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available