Journal
PARASITES & VECTORS
Volume 4, Issue -, Pages -Publisher
BMC
DOI: 10.1186/1756-3305-4-194
Keywords
Schistosomiasis; Schistosoma japonicum; Parasitological examination; Immunodiagnosis; Chemotherapy
Categories
Funding
- National High Technology Research and Development Program of China [2006AA02Z402]
- National S & T Major Program [2008ZX10004-011]
- National Natural Science Foundation of China [30590374]
- Shanghai Leading Academic Discipline [B118]
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Worldwide schistosomiasis continues to be a serious public health problem. Over the past five decades, China has made remarkable progress in reducing Schistosoma japonicum infections in humans to a relatively low level. Endemic regions are currently circumscribed in certain core areas where re-infection and repeated chemotherapy are frequent. At present, selective chemotherapy with praziquantel is one of the main strategies in China's National Schistosomiasis Control Program, and thus diagnosis of infected individuals is a key step for such control. In this paper we review the current status of our knowledge about diagnostic tools for schistosomiasis japonica. A simple, affordable, sensitive, and specific assay for field diagnosis of schistosomiasis japonica is not yet available, and this poses great barriers towards full control of schistosomiasis. Hence, a search for a diagnostic approach, which delivers these characteristics, is essential and should be given high priority.
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