Journal
PAEDIATRIC RESPIRATORY REVIEWS
Volume 9, Issue 3, Pages 213-219Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.prrv.2008.04.003
Keywords
sinusitis; nasal polyps; cystic fibrosis; Pseudomonas; lung transplantation; sinus surgery; mucocele
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Pal and sinus disease is present in almost every patient with cystic fibrosis. However, symptoms are rarely reported. Some aspects including polyposis and microbial flora change with patient age. Endoscopy and computerised tomography have broadened our understanding of how this disease affects the sinuses, including an increased recognition of polyposis than previously thought and identification of several disease specific entities such as abnormalities of the lateral nasal wall and uncinate process. Few randomised, controlled trials evaluating medical or surgical treatments of CF sinus disease exist. Sinus surgery may provide some benefit, though there are no established selection criteria for appropriate candidates. A link between sinus disease and lower respiratory tract function may contribute to general health and survival following lung transplantation. Complications of sinonasal disease in CF are rare and include mucoceles and periorbital abscesses. (c) 2008 Elsevier Ltd. All rights reserved.
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